PEX6

Across TCGA patient cohorts, PEX6 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,621 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PEX6-associated proteins across cancer lineages are PEX1, RPS6, and ISG20. Each is linked with PEX6 in more than 4 cancer types. Because this analysis shows association rather than direction, both PEX6-to-partner and partner-to-PEX6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PEX6 versus PEX1 in LSCC, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PEX6→partner) and Y-score (partner→PEX6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PEX1 →	+0.349	+0.745	<.001	<.001	3	5
GBM	RPS6 →	-0.398	-0.349	.002	.003	3	4
BRCA	ISG20 →	-0.427	-0.560	.002	.001	3	4
LSCC	CRELD2 →	-0.515	-0.878	<.001	<.001	3	4
HNSC	ZNF318_S2101 →	+0.435	+0.967	<.001	<.001	3	3
LUAD	MZB1 →	-0.640	-0.647	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,621 associations by consensus.

PEX6 vs PEX1 — LSCC

Explore this scatter interactively →