PEX5L-AS1

Across TCGA pan-cancer cohorts, PEX5L-AS1 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated PEX5L-AS1 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher PEX5L-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PEX5L-AS1 expression acts as an unfavorable survival marker, although some lineages such as ESCA and MESO show a favorable association.

BLCA, ACC, and STAD are the cancer types where PEX5L-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Tertile	All	0.487	0.641	.007	75	view →
ACC	OS	Tertile	All	0.134	0.727	<.001	72	view →
STAD	OS	Tertile	All	0.286	0.583	.001	66	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	36	view →
ESCA	DFS	Tertile	III,IV	0.763	0.369	.023	36	view →
LIHC	OS	Tertile	III,IV	0.148	0.633	<.001	36	view →
MESO	OS	Median	IV	0.822	0.339	.002	33	view →
CHOL	OS	Tertile	All	0.089	0.673	.018	18	view →
TGCT	DFS	Tertile	II,III,IV	0.560	0.949	.024	18	view →
LGG	OS	Quartile	All	0.717	0.847	.002	14	view →
KIRC	DFS	Tertile	IV	0.789	0.516	.044	12	view →
PRAD	OS	Tertile	All	0.963	0.997	.008	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

PEX5L-AS1–BLCA (DFS)

Open the BLCA breakdown →