Across TCGA pan-cancer cohorts, PEX26 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated PEX26 data layer compared with 22 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher PEX26 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated PEX26 expression acts as an unfavorable survival marker.

SKCM and ESCA are the cancer types where PEX26 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Median	All	0.046	0.757	<.001	9	view →
ESCA	DFS	Median	II,III,IV	0.149	0.522	.047	3	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: PEX26 tumor-vs-normal RNA expression · all PEX26 data types