PEX19

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PEX19 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,311 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PEX19-associated GO terms across cancer lineages are Regulation of protein sumoylation, Cytosolic transport, and Regulation of transcription initiation by RNA polymerase II. Each is linked with PEX19 in more than 13 cancer types. Because this analysis shows association rather than direction, both PEX19-to-partner and partner-to-PEX19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein sumoylation grouped by PEX19-low versus PEX19-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PEX19→partner) and Y-score (partner→PEX19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUERegulation of protein sumoylation →+0.103+0.888.001<.001314
UPPER_AERODIGESTIVE_TRACTCytosolic transport →+0.065+0.892.003.009313
SOFT_TISSUERegulation of transcription initiation by RNA polymerase II →+0.066+0.769<.001<.001313
STOMACHRegulation of smoothened signaling pathway →+0.044+0.633<.001<.001313
OESOPHAGUSRegulation of DNA-templated transcription initiation →+0.066+0.709.007.003313
UPPER_AERODIGESTIVE_TRACTPositive regulation of DNA-templated transcription initiation →+0.073+0.951.002.006313
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,311 associations by consensus.

Regulation of protein sumoylation by PEX19 expression — SOFT_TISSUE

Box plot of Regulation of protein sumoylation in PEX19-low vs PEX19-high samples in SOFT_TISSUE.

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