PEX14

Across TCGA patient cohorts, PEX14 protein abundance is significantly associated with the RNA expression of many other genes, with 8,512 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible PEX14-associated genes across cancer lineages are EXOSC10, SSU72, and DFFA. Each is linked with PEX14 in more than 5 cancer types. Because this analysis shows association rather than direction, both PEX14-to-partner and partner-to-PEX14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PEX14 versus EXOSC10 in OV, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PEX14→partner) and Y-score (partner→PEX14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	EXOSC10 →	+0.513	+0.274	<.001	<.001	3	6
OV	SSU72 →	+0.355	+0.324	.007	.002	3	6
LUAD	DFFA →	+0.529	+0.441	<.001	<.001	3	5
OV	LZIC →	+0.450	+0.404	<.001	<.001	3	5
HNSC	CDC42 →	+0.448	+0.291	<.001	.002	3	5
LUAD	EMC1 →	+0.561	+0.389	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,512 associations by consensus.

PEX14 vs EXOSC10 — OV

Explore this scatter interactively →