PEX11B

Across TCGA pan-cancer cohorts, PEX11B Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated PEX11B data layer compared with 20 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher PEX11B Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated PEX11B expression acts as an unfavorable survival marker.

CESC, PRAD, and SKCM are the cancer types where PEX11B Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	OS	Median	All	0.203	0.798	.001	18	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
SKCM	OS	Median	II,III,IV	0.202	0.739	.004	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

PEX11B–CESC (OS)

Open the CESC breakdown →