PEX10

Across TCGA pan-cancer cohorts, PEX10 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated PEX10 data layer compared with 23 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher PEX10 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated PEX10 expression acts as an unfavorable survival marker, although some lineages such as PDAC and GBM show a favorable association.

HNSC, PDAC, and LUAD are the cancer types where PEX10 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Quartile	All	0.641	1.000	.013	13	view →
PDAC	DFS	Median	II,III,IV	0.734	0.389	.004	11	view →
LUAD	OS	Quartile	All	0.357	0.825	.017	8	view →
GBM	DFS	Quartile	All	0.471	0.235	.021	7	view →
CCRCC	DFS	Median	All	1.000	0.901	.031	5	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

PEX10–HNSC (OS)

Open the HNSC breakdown →