PEX10

Across TCGA cell cohorts, PEX10 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,750 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PEX10-associated GO terms across cancer lineages are Protein import into peroxisome matrix, substrate release, Pre-mRNA catabolic process, and Positive regulation of intracellular estrogen receptor signaling pathway. Each is linked with PEX10 in more than 17 cancer types. Because this analysis shows association rather than direction, both PEX10-to-partner and partner-to-PEX10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein import into peroxisome matrix, substrate release grouped by PEX10-low versus PEX10-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PEX10→partner) and Y-score (partner→PEX10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Protein import into peroxisome matrix, substrate release →	+0.163	+0.745	.001	<.001	3	18
BONE	Pre-mRNA catabolic process →	+0.192	+0.592	.001	.002	3	12
UPPER_AERODIGESTIVE_TRACT	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.162	+0.902	<.001	<.001	3	11
OESOPHAGUS	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.149	+0.703	<.001	<.001	2	11
BONE	Transcription pausing by RNA polymerase II →	+0.144	+0.696	<.001	<.001	3	10
KIDNEY	Regulation of Golgi inheritance →	+0.148	+0.841	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,750 associations by consensus.

Protein import into peroxisome matrix, substrate release by PEX10 expression — OESOPHAGUS

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