PEX1

Across TCGA cell cohorts, PEX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,935 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PEX1-associated GO terms across cancer lineages are Sperm motility, Flagellated sperm motility, and Cilium movement involved in cell motility. Each is linked with PEX1 in more than 14 cancer types. Because this analysis shows association rather than direction, both PEX1-to-partner and partner-to-PEX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sperm motility grouped by PEX1-low versus PEX1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PEX1→partner) and Y-score (partner→PEX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Sperm motility →	-0.114	-1.022	<.001	.001	3	15
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.114	-1.022	<.001	.001	3	15
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.108	-1.041	<.001	.001	3	15
LIVER	Protein targeting to peroxisome →	+0.112	+0.868	<.001	.008	3	15
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.103	-1.053	<.001	.001	3	14
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.103	-1.053	<.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,935 associations by consensus.

Sperm motility by PEX1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →