PET117

Across TCGA patient cohorts, PET117 protein abundance is significantly associated with the RNA expression of many other genes, with 8,695 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PET117-associated genes across cancer lineages are NRP1, MGME1, and COX5A. Each is linked with PET117 in more than 3 cancer types. Because this analysis shows association rather than direction, both PET117-to-partner and partner-to-PET117 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PET117 versus NRP1 in BRCA, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PET117→partner) and Y-score (partner→PET117) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NRP1 →	-0.817	-0.746	<.001	<.001	3	4
LSCC	MGME1 →	+0.827	+0.563	<.001	<.001	3	4
LSCC	COX5A →	+0.433	+0.325	<.001	<.001	3	4
LSCC	PGAM5 →	+0.531	+0.364	.001	.001	3	4
LSCC	TRMT6 →	+0.691	+0.535	<.001	<.001	3	4
GBM	BIRC5 →	+1.506	+0.428	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,695 associations by consensus.

PET117 vs NRP1 — BRCA

Explore this scatter interactively →