Across TCGA pan-cancer cohorts, PET100 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated PET100 data layer compared with 28 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher PET100 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated PET100 expression acts as an unfavorable survival marker, although some lineages such as LSCC and PDAC show a favorable association.

LSCC, HNSC, and PDAC are the cancer types where PET100 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Tertile	All	0.917	0.637	.001	32	view →
HNSC	OS	Tertile	All	0.349	1.000	.040	20	view →
PDAC	DFS	Median	III,IV	0.933	0.463	.012	10	view →
GBM	OS	Tertile	All	0.681	0.371	.013	4	view →
CCRCC	OS	Quartile	All	0.960	0.766	.017	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: PET100 tumor-vs-normal RNA expression · all PET100 data types