PES1P1

Across TCGA pan-cancer cohorts, PES1P1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of PES1P1’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where PES1P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PES1P1 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

LIHC, COAD, and KIRC are the cancer types where PES1P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PES1P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Male	All	+0.275	<.001	6	view →
COAD	All	II,III,IV	+0.045	.026	4	view →
KIRC	All	III,IV	−0.005	.042	4	view →
LUAD	All	All	+0.051	.041	2	view →
STAD	All	II,III,IV	+0.017	.043	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

PES1P1–LIHC

Open the LIHC breakdown →