PERP

Across TCGA patient cohorts, PERP protein abundance is significantly associated with the RNA expression of many other genes, with 2,137 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PERP-associated genes across cancer lineages are RHOXF1, LAX1, and ANKRD36. Each is linked with PERP in more than 1 cancer types. Because this analysis shows association rather than direction, both PERP-to-partner and partner-to-PERP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PERP versus RHOXF1 in HNSC, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PERP→partner) and Y-score (partner→PERP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RHOXF1 →	-0.394	-0.837	.003	<.001	3	2
HNSC	LAX1 →	-1.034	-0.465	.001	.009	3	2
HNSC	ANKRD36 →	-0.818	-0.575	.002	.001	3	2
COAD	RHBDD1 →	-0.519	-0.786	.001	.003	3	2
HNSC	CYP4V2 →	-0.706	-0.687	.001	<.001	3	2
COAD	SPRY3 →	-0.479	-0.820	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,137 associations by consensus.

PERP vs RHOXF1 — HNSC

Explore this scatter interactively →