PERP

Across TCGA patient cohorts, PERP mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible PERP-associated genes across cancer lineages are Adipocytes and CD8+ Tem. Each is linked with PERP in more than 1 cancer types. Because this analysis shows association rather than direction, both PERP-to-partner and partner-to-PERP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Adipocytes grouped by PERP-low versus PERP-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PERP→partner) and Y-score (partner→PERP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Adipocytes →	+0.042	+3.178	.013	.049	3	1
UCEC	CD8+ Tem →	+0.004	+4.744	<.001	.040	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Adipocytes by PERP expression — SKCM

Explore this box plot interactively →