Across TCGA cell cohorts, PERM1 RNA expression is significantly associated with the RNA expression of many other genes, with 10,313 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PERM1-associated genes across cancer lineages are PLEKHN1, AGRN, and HES4. Each is linked with PERM1 in more than 19 cancer types. Because this analysis shows association rather than direction, both PERM1-to-partner and partner-to-PERM1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PERM1→partner) and Y-score (partner→PERM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	PLEKHN1 →	+1.624	+1.134	<.001	<.001	3	20
LUNG_SCLC	AGRN →	+2.778	+0.526	<.001	<.001	3	16
LUNG_SCLC	HES4 →	+2.511	+0.517	<.001	.001	3	12
BONE	PLEC →	+1.686	+0.366	<.001	.001	3	12
STOMACH	MROH1 →	+1.373	+0.970	<.001	<.001	3	12
LIVER	PKP3 →	+3.629	+1.035	<.001	<.001	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,313 associations by consensus.

Exploration

PERM1 survival (RNA) · tumor vs normal (RNA) · all PERM1 data types