PER3P1

Across TCGA pan-cancer cohorts, PER3P1 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated PER3P1 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher PER3P1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PER3P1 expression acts as an unfavorable survival marker, although some lineages such as OV show a favorable association.

KIRP, LGG, and READ are the cancer types where PER3P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Tertile	All	0.356	0.865	<.001	102	view →
LGG	OS	Tertile	All	0.468	0.834	<.001	54	view →
READ	DFS	Tertile	All	0.233	0.703	.002	39	view →
BRCA	OS	Tertile	IV	0.233	0.755	.038	36	view →
LIHC	OS	Tertile	III,IV	0.051	0.650	<.001	36	view →
ACC	OS	Tertile	All	0.133	0.686	.004	36	view →
PAAD	OS	Tertile	All	0.180	0.645	.004	18	view →
ESCA	DFS	Tertile	II,III,IV	0.131	0.776	.043	9	view →
OV	DFS	Tertile	All	0.743	0.531	.036	6	view →
SARC	OS	Tertile	All	0.181	0.595	.032	6	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

PER3P1–KIRP (DFS)

Open the KIRP breakdown →