PER2

Across TCGA pan-cancer cohorts, PER2 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated PER2 data layer compared with 23 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher PER2 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated PER2 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC and CCRCC are the cancer types where PER2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Quartile	All	1.000	0.748	.003	26	view →
CCRCC	DFS	Median	III,IV	0.295	0.740	.049	2	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

PER2–UCEC (OS)

Open the UCEC breakdown →