PER2

Across TCGA patient cohorts, PER2 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,816 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PER2-associated proteins across cancer lineages are RIPK2, SH3BP4, and SH3BP4_S246. Each is linked with PER2 in more than 3 cancer types. Because this analysis shows association rather than direction, both PER2-to-partner and partner-to-PER2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PER2 versus RIPK2 in CCRCC, with a Pearson correlation of -0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PER2→partner) and Y-score (partner→PER2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	RIPK2 →	-0.267	-0.646	<.001	<.001	3	4
BRCA	SH3BP4 →	+0.391	+0.698	<.001	<.001	3	4
BRCA	SH3BP4_S246 →	+0.982	+0.695	<.001	.002	3	4
LSCC	SPCS3 →	-0.364	-0.365	<.001	.002	3	4
BRCA	SRPRA →	-0.335	-0.738	<.001	<.001	3	4
LSCC	AGAP1 →	+0.274	+0.530	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,816 associations by consensus.

PER2 vs RIPK2 — CCRCC

Explore this scatter interactively →