PER1

Across TCGA patient cohorts, PER1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,327 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PER1-associated genes across cancer lineages are BCL11B, HIF3A, and SATB2-AS1. Each is linked with PER1 in more than 2 cancer types. Because this analysis shows association rather than direction, both PER1-to-partner and partner-to-PER1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PER1 versus BCL11B in PDAC, with a Pearson correlation of -0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PER1→partner) and Y-score (partner→PER1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	BCL11B →	-0.576	-0.253	<.001	.006	3	3
GBM	HIF3A →	+1.333	+0.484	<.001	<.001	3	3
GBM	SATB2-AS1 →	+0.578	+0.347	.001	.001	3	2
UCEC	KLF13 →	-0.635	-0.441	.007	.005	3	2
GBM	PLPP4 →	-1.141	-0.397	<.001	<.001	3	2
HNSC	FAM241B →	-1.046	-0.481	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,327 associations by consensus.

PER1 vs BCL11B — PDAC

Explore this scatter interactively →