PEMT

Across TCGA patient cohorts, PEMT protein abundance is significantly associated with the protein abundance of many other proteins, with 3,082 significant associations in total. OV shows the largest number of these associations.

The most reproducible PEMT-associated proteins across cancer lineages are PCM1_S861, FAM91A1_S355, and ASH2L_S101. Each is linked with PEMT in more than 1 cancer types. Because this analysis shows association rather than direction, both PEMT-to-partner and partner-to-PEMT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PEMT versus PCM1_S861 in GBM, with a Pearson correlation of -0.57.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PEMT→partner) and Y-score (partner→PEMT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PCM1_S861 →	-1.139	-0.783	<.001	.002	3	2
OV	FAM91A1_S355 →	-1.736	-0.743	<.001	.002	3	2
HNSC	ASH2L_S101 →	+1.020	+0.620	.004	<.001	3	2
HNSC	SIK2_T484 →	-1.481	-0.620	<.001	<.001	3	2
HNSC	PHRF1_S867 →	-1.064	-0.631	<.001	<.001	3	2
HNSC	PABPN1_S95 →	-1.833	-0.657	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,082 associations by consensus.

PEMT vs PCM1_S861 — GBM

Explore this scatter interactively →