PELP1

Across TCGA pan-cancer cohorts, PELP1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated PELP1 data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher PELP1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated PELP1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and HNSC show a favorable association.

PDAC, LSCC, and HNSC are the cancer types where PELP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Quartile	All	0.620	0.855	<.001	47	view →
LSCC	DFS	Median	II,III,IV	0.879	0.541	.005	14	view →
HNSC	DFS	Median	II,III,IV	0.972	0.899	.032	4	view →
LUAD	DFS	Quartile	All	0.581	1.000	.029	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

PELP1–PDAC (DFS)

Open the PDAC breakdown →