PELP1

Across TCGA patient cohorts, PELP1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,457 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PELP1-associated genes across cancer lineages are TEX10, MTPAP, and E2F3. Each is linked with PELP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PELP1-to-partner and partner-to-PELP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PELP1 versus TEX10 in LSCC, with a Pearson correlation of 0.75.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PELP1→partner) and Y-score (partner→PELP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TEX10 →	+0.788	+0.361	<.001	<.001	3	7
HNSC	MTPAP →	+0.475	+0.164	<.001	<.001	3	5
LSCC	E2F3 →	+0.619	+0.178	<.001	<.001	3	5
HNSC	IL9R →	-0.382	-0.167	.008	<.001	3	5
HNSC	MYBBP1A →	+0.701	+0.174	.003	.003	3	5
HNSC	RAB37 →	-0.614	-0.159	.006	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,457 associations by consensus.

PELP1 vs TEX10 — LSCC

Explore this scatter interactively →