PELP1

Across TCGA cell cohorts, PELP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,431 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PELP1-associated GO terms across cancer lineages are 'de novo' IMP biosynthetic process, RNA export from nucleus, and Regulation of G1 to G0 transition. Each is linked with PELP1 in more than 16 cancer types. Because this analysis shows association rather than direction, both PELP1-to-partner and partner-to-PELP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 'de novo' IMP biosynthetic process grouped by PELP1-low versus PELP1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PELP1→partner) and Y-score (partner→PELP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	'de novo' IMP biosynthetic process →	+0.208	+1.061	<.001	<.001	3	17
BONE	RNA export from nucleus →	+0.151	+0.935	<.001	<.001	3	17
LUNG_SCLC	Regulation of G1 to G0 transition →	+0.178	+0.798	<.001	.001	3	17
BONE	Cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.158	+0.693	<.001	<.001	3	16
BONE	Nucleic acid transport →	+0.120	+0.918	<.001	<.001	3	16
BONE	RNA transport →	+0.120	+0.918	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,431 associations by consensus.

'de novo' IMP biosynthetic process by PELP1 expression — BONE

Explore this box plot interactively →