PELI3

Across TCGA cell cohorts, PELI3 RNA expression is significantly associated with the RNA expression of many other genes, with 10,844 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PELI3-associated genes across cancer lineages are KLC2, AP5B1, and CCS. Each is linked with PELI3 in more than 14 cancer types. Because this analysis shows association rather than direction, both PELI3-to-partner and partner-to-PELI3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PELI3 versus KLC2 in URINARY_TRACT, with a Pearson correlation of 0.66.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PELI3→partner) and Y-score (partner→PELI3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	KLC2 →	+1.256	+1.197	<.001	<.001	3	15
LARGE_INTESTINE	AP5B1 →	+1.227	+0.839	<.001	<.001	3	13
OESOPHAGUS	CCS →	+1.361	+1.203	.001	<.001	2	13
LUNG_NSCLC_LUSC	ZDHHC24 →	+0.839	+0.831	<.001	<.001	3	12
STOMACH	FAM168A →	+1.279	+1.046	<.001	<.001	3	12
LARGE_INTESTINE	PHRF1 →	+1.159	+0.794	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,844 associations by consensus.

PELI3 vs KLC2 — URINARY_TRACT

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