PELI3

Across TCGA cell cohorts, PELI3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,851 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PELI3-associated GO terms across cancer lineages are CTP salvage, Positive regulation of anaphase-promoting complex-dependent catabolic process, and Regulation of centriole-centriole cohesion. Each is linked with PELI3 in more than 11 cancer types. Because this analysis shows association rather than direction, both PELI3-to-partner and partner-to-PELI3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CTP salvage grouped by PELI3-low versus PELI3-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PELI3→partner) and Y-score (partner→PELI3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	CTP salvage →	+0.119	+0.764	<.001	.001	3	12
BONE	Positive regulation of anaphase-promoting complex-dependent catabolic process →	+0.124	+0.749	.004	.003	2	12
LARGE_INTESTINE	Regulation of centriole-centriole cohesion →	+0.135	+0.577	<.001	.003	3	11
OVARY	Interleukin-34-mediated signaling pathway →	+0.207	+0.966	<.001	<.001	3	11
SOFT_TISSUE	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.118	+0.601	.004	.005	2	12
LUNG_SCLC	Regulation of protein localization to centrosome →	+0.106	+0.582	.001	.005	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,851 associations by consensus.

CTP salvage by PELI3 expression — OVARY

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