PELI1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PELI1 mutation is significantly associated with the RNA expression of many other genes, with 2,324 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PELI1-associated genes across cancer lineages are RNA5SP419, RNA5SP414, and FAM177A1. Each is linked with PELI1 in more than 2 cancer types. Because this analysis shows association rather than direction, both PELI1-to-partner and partner-to-PELI1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PELI1→partner) and Y-score (partner→PELI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP419 →+0.836+2.698<.001<.00133
UCECRNA5SP414 →+0.555+2.348<.001<.00132
UCECFAM177A1 →+0.467+3.732<.001<.00132
UCECLIN7B →+0.408+1.858.006.00532
UCECACYP1 →+0.472+2.269.001.00132
UCECANXA1 →+1.090+2.230.001.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,324 associations by consensus.

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