Across TCGA patient cohorts, PEG3 mutation is significantly associated with the RNA expression of many other genes, with 9,997 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PEG3-associated genes across cancer lineages are OIP5, ZNF367, and BRIP1. Each is linked with PEG3 in more than 6 cancer types. Because this analysis shows association rather than direction, both PEG3-to-partner and partner-to-PEG3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PEG3→partner) and Y-score (partner→PEG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	OIP5 →	+0.691	+1.935	<.001	<.001	3	7
UCEC	ZNF367 →	+0.611	+1.523	<.001	<.001	3	7
LUAD	BRIP1 →	+0.387	+1.726	.001	<.001	3	7
UCEC	HASPIN →	+0.727	+1.647	<.001	<.001	3	7
UCEC	CHAF1A →	+0.645	+2.579	<.001	<.001	3	7
STAD	KNL1 →	+0.538	+3.807	.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,997 associations by consensus.

Exploration

PEG3 survival (RNA) · tumor vs normal (RNA) · all PEG3 data types