Across TCGA patient cohorts, PEG3 mutation is significantly associated with the total protein of many other genes, with 105 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PEG3-associated genes across cancer lineages are PCNA, Cyclin-E2, and 4E-BP1. Each is linked with PEG3 in more than 5 cancer types. Because this analysis shows association rather than direction, both PEG3-to-partner and partner-to-PEG3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PEG3→partner) and Y-score (partner→PEG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	PCNA →	+0.306	+2.392	<.001	<.001	3	6
STAD	Cyclin-E2 →	+0.109	+2.021	.011	.014	3	6
BLCA	4E-BP1 →	+0.338	+2.321	.002	.033	3	6
ESCA	Caveolin-1 →	-0.854	-3.321	.001	.007	3	5
BRCA	FoxM1 →	+0.379	+3.169	.017	.020	3	5
BRCA	ASNS →	+0.356	+2.321	.039	.037	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 105 associations by consensus.

Exploration

PEG3 survival (RNA) · tumor vs normal (RNA) · all PEG3 data types