PEF1

Across TCGA cell cohorts, PEF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,765 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PEF1-associated GO terms across cancer lineages are Transport of virus, Intracellular transport of virus, and Organelle transport along microtubule. Each is linked with PEF1 in more than 11 cancer types. Because this analysis shows association rather than direction, both PEF1-to-partner and partner-to-PEF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transport of virus grouped by PEF1-low versus PEF1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PEF1→partner) and Y-score (partner→PEF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Transport of virus →	+0.194	+0.701	.009	.009	2	12
LUNG_NSCLC_LUSC	Intracellular transport of virus →	+0.194	+0.701	.009	.009	2	12
LIVER	Organelle transport along microtubule →	+0.066	+0.431	.008	.004	3	10
URINARY_TRACT	Negative regulation of plasma membrane bounded cell projection assembly →	+0.073	+0.818	.005	<.001	3	9
STOMACH	Regulation of protein monoubiquitination →	+0.129	+0.460	.002	.005	2	9
STOMACH	Positive regulation of protein monoubiquitination →	+0.129	+0.460	.002	.005	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,765 associations by consensus.

Transport of virus by PEF1 expression — LUNG_NSCLC_LUSC

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