PEDS1

Across TCGA patient cohorts, PEDS1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,739 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PEDS1-associated genes across cancer lineages are CD40LG, GRAP2, and CHRDL1. Each is linked with PEDS1 in more than 4 cancer types. Because this analysis shows association rather than direction, both PEDS1-to-partner and partner-to-PEDS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PEDS1 versus CD40LG in LUAD, with a Pearson correlation of -0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PEDS1→partner) and Y-score (partner→PEDS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CD40LG →	-0.932	-0.671	<.001	<.001	3	5
HNSC	GRAP2 →	-0.808	-0.479	<.001	.002	3	4
PDAC	CHRDL1 →	-1.497	-0.610	.004	.002	3	4
HNSC	TNXB →	-1.119	-0.563	<.001	<.001	3	4
HNSC	GNG7 →	-0.495	-0.474	<.001	.001	3	4
LUAD	MIR29B2CHG →	-0.759	-0.516	.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,739 associations by consensus.

PEDS1 vs CD40LG — LUAD

Explore this scatter interactively →