PEDS1-UBE2V1

Across TCGA pan-cancer cohorts, PEDS1-UBE2V1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated PEDS1-UBE2V1 data layer compared with 16 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher PEDS1-UBE2V1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated PEDS1-UBE2V1 expression acts as an unfavorable survival marker, although some lineages such as GBM and HNSC show a favorable association.

CCRCC, GBM, and LUAD are the cancer types where PEDS1-UBE2V1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	All	0.905	1.000	.013	10	view →
GBM	OS	Median	All	0.656	0.414	.007	6	view →
LUAD	DFS	Median	All	0.891	1.000	.014	6	view →
HNSC	DFS	Tertile	II,III,IV	0.848	0.687	.035	4	view →
PDAC	DFS	Median	III,IV	0.453	0.252	.049	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

PEDS1-UBE2V1–CCRCC (OS)

Open the CCRCC breakdown →