PECAM1

Across TCGA pan-cancer cohorts, PECAM1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated PECAM1 data layer compared with 25 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher PECAM1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated PECAM1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

UCEC, CCRCC, and LUAD are the cancer types where PECAM1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.748	0.983	<.001	20	view →
CCRCC	DFS	Tertile	III,IV	0.829	0.444	.003	19	view →
LUAD	DFS	Tertile	III,IV	0.240	0.995	.002	16	view →
HNSC	DFS	Tertile	All	0.924	1.000	.015	5	view →
PDAC	OS	Median	III,IV	0.537	1.000	.008	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

PECAM1–UCEC (DFS)

Open the UCEC breakdown →