PECAM1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PECAM1 protein abundance is significantly associated with the RNA expression of many other genes, with 20,857 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PECAM1-associated genes across cancer lineages are CLEC1A, FLI1, and GMFG. Each is linked with PECAM1 in more than 9 cancer types. Because this analysis shows association rather than direction, both PECAM1-to-partner and partner-to-PECAM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PECAM1 versus CLEC1A in CCRCC, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PECAM1→partner) and Y-score (partner→PECAM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CCRCCCLEC1A →+0.970+0.495<.001<.001310
LSCCFLI1 →+0.819+0.548<.001<.001310
GBMGMFG →+0.993+0.415<.001<.00139
BRCAGIMAP6 →+1.029+0.472<.001<.00139
CCRCCDIPK2B →+1.116+0.535<.001<.00139
LSCCCYSLTR1 →+0.863+0.569<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 20,857 associations by consensus.

PECAM1 vs CLEC1A — CCRCC

Per-sample scatter of PECAM1 vs CLEC1A in CCRCC (Pearson r = 0.67).

Explore this scatter interactively →

Exploration