PECAM1

Across TCGA cell cohorts, PECAM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,127 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PECAM1-associated GO terms across cancer lineages are Viral process, Multi-pass transmembrane protein insertion into ER membrane, and Regulation of myoblast fusion. Each is linked with PECAM1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PECAM1-to-partner and partner-to-PECAM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral process grouped by PECAM1-low versus PECAM1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PECAM1→partner) and Y-score (partner→PECAM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Viral process →	+0.063	+0.253	.004	<.001	3	7
LARGE_INTESTINE	Multi-pass transmembrane protein insertion into ER membrane →	+0.051	+0.146	.007	.003	3	6
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.083	+0.168	.002	.001	3	6
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.093	+0.169	<.001	<.001	3	6
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.089	+0.140	.003	.002	3	6
BLOOD_Lymphoma	Negative regulation of RNA splicing →	+0.068	+1.065	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,127 associations by consensus.

Viral process by PECAM1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →