PEAR1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PEAR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,756 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PEAR1-associated GO terms across cancer lineages are Urokinase plasminogen activator signaling pathway, Cellular response to abiotic stimulus, and Cellular response to environmental stimulus. Each is linked with PEAR1 in more than 10 cancer types. Because this analysis shows association rather than direction, both PEAR1-to-partner and partner-to-PEAR1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PEAR1→partner) and Y-score (partner→PEAR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHUrokinase plasminogen activator signaling pathway →+0.962+1.314.006.002311
OESOPHAGUSCellular response to abiotic stimulus →+0.047+1.987<.001<.001311
OESOPHAGUSCellular response to environmental stimulus →+0.047+1.987<.001<.001311
PANCREASDentinogenesis →+1.490+1.690<.001.003310
LUNG_NSCLC_LUSCRegulation of cell-substrate adhesion →+0.088+2.014<.001.004310
BLOOD_LeukemiaSkeletal myofibril assembly →+0.627+1.429<.001<.001310
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,756 associations by consensus.

Exploration