Across TCGA patient cohorts, PEAK3 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,339 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PEAK3-associated proteins across cancer lineages are ARHGAP45, WIPF1, and RASA3. Each is linked with PEAK3 in more than 7 cancer types. Because this analysis shows association rather than direction, both PEAK3-to-partner and partner-to-PEAK3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PEAK3→partner) and Y-score (partner→PEAK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ARHGAP45 →	+0.477	+0.525	.001	<.001	3	7
OV	WIPF1 →	+0.395	+0.183	.004	.004	2	8
UCEC	RASA3 →	+0.437	+0.688	<.001	.004	3	7
GBM	ARHGAP9 →	+0.419	+0.560	.002	<.001	2	7
LSCC	GIMAP1 →	+0.502	+0.327	<.001	<.001	3	6
OV	GNG2 →	+0.693	+0.231	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,339 associations by consensus.

Exploration

PEAK3 survival (RNA) · tumor vs normal (RNA) · all PEAK3 data types