Across TCGA patient cohorts, PEAK3 protein abundance is significantly associated with the RNA expression of many other genes, with 6,774 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PEAK3-associated genes across cancer lineages are MEFV, FCGR3B, and AQP9. Each is linked with PEAK3 in more than 3 cancer types. Because this analysis shows association rather than direction, both PEAK3-to-partner and partner-to-PEAK3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PEAK3→partner) and Y-score (partner→PEAK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	MEFV →	+1.231	+1.443	.004	<.001	3	4
PDAC	FCGR3B →	+2.379	+1.203	<.001	<.001	3	4
PDAC	AQP9 →	+1.439	+1.087	.001	.001	3	3
PDAC	HLF →	-0.986	-1.050	<.001	.002	3	3
LUAD	PLAUR →	+1.152	+0.709	<.001	<.001	3	3
PDAC	BCL2A1 →	+1.511	+1.306	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,774 associations by consensus.

Exploration

PEAK3 survival (RNA) · tumor vs normal (RNA) · all PEAK3 data types