PEAK1

Across TCGA patient cohorts, PEAK1 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,879 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible PEAK1-associated proteins across cancer lineages are MMP2, HTRA1, and TIMP2. Each is linked with PEAK1 in more than 8 cancer types. Because this analysis shows association rather than direction, both PEAK1-to-partner and partner-to-PEAK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PEAK1 versus MMP2 in BRCA, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PEAK1→partner) and Y-score (partner→PEAK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MMP2 →	+0.739	+0.703	<.001	<.001	3	9
LSCC	HTRA1 →	+0.854	+0.656	<.001	<.001	3	8
BRCA	TIMP2 →	+0.711	+0.628	<.001	<.001	3	8
OV	PRKG1 →	+0.624	+0.998	.001	<.001	3	8
BRCA	SGCD →	+0.581	+0.717	<.001	<.001	3	8
BRCA	HMCN1 →	+0.676	+0.672	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,879 associations by consensus.

PEAK1 vs MMP2 — BRCA

Explore this scatter interactively →