PEAK1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PEAK1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,942 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PEAK1-associated genes across cancer lineages are LAMA4, CNRIP1, and ZEB1. Each is linked with PEAK1 in more than 8 cancer types. Because this analysis shows association rather than direction, both PEAK1-to-partner and partner-to-PEAK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PEAK1 versus LAMA4 in BRCA, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PEAK1→partner) and Y-score (partner→PEAK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCALAMA4 →+1.093+0.349<.001<.00139
BRCACNRIP1 →+0.964+0.305<.001<.00139
BRCAZEB1 →+1.127+0.314<.001<.00139
BRCAZCCHC24 →+1.001+0.241<.001<.00139
CCRCCJAM3 →+1.030+0.377<.001<.00139
BRCALHFPL6 →+1.089+0.235<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,942 associations by consensus.

PEAK1 vs LAMA4 — BRCA

Per-sample scatter of PEAK1 vs LAMA4 in BRCA (Pearson r = 0.62).

Explore this scatter interactively →

Exploration