PDZRN3

Across TCGA patient cohorts, PDZRN3 protein abundance is significantly associated with the RNA expression of many other genes, with 9,363 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PDZRN3-associated genes across cancer lineages are GLT8D2, HSPA12B, and MSRB3. Each is linked with PDZRN3 in more than 5 cancer types. Because this analysis shows association rather than direction, both PDZRN3-to-partner and partner-to-PDZRN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDZRN3 versus GLT8D2 in BRCA, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDZRN3→partner) and Y-score (partner→PDZRN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GLT8D2 →	+1.174	+0.511	<.001	<.001	3	6
UCEC	HSPA12B →	+0.661	+0.249	<.001	.009	3	6
BRCA	MSRB3 →	+1.239	+0.537	<.001	<.001	3	6
HNSC	MEIS3 →	+1.191	+0.581	<.001	<.001	3	5
HNSC	PCOLCE →	+0.952	+0.505	.005	<.001	3	5
HNSC	CXCL12 →	+1.207	+0.575	.002	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,363 associations by consensus.

PDZRN3 vs GLT8D2 — BRCA

Explore this scatter interactively →