PDZRN3

Across TCGA patient cohorts, PDZRN3 mutation is significantly associated with the RNA expression of many other genes, with 4,844 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PDZRN3-associated genes across cancer lineages are TAF13, TSPY26P, and RNU2-27P. Each is linked with PDZRN3 in more than 3 cancer types. Because this analysis shows association rather than direction, both PDZRN3-to-partner and partner-to-PDZRN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAF13 grouped by PDZRN3-low versus PDZRN3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDZRN3→partner) and Y-score (partner→PDZRN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TAF13 →	+0.644	+2.544	<.001	<.001	3	4
SKCM	TSPY26P →	-0.801	-2.395	.008	.003	3	4
COAD	RNU2-27P →	+0.731	+3.383	.004	.004	3	4
COAD	PIAS2 →	+0.490	+3.509	<.001	.002	3	4
HNSC	THOC1 →	+0.689	+2.291	<.001	.005	3	3
HNSC	NDUFB4 →	+0.450	+3.476	.002	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,844 associations by consensus.

TAF13 by PDZRN3 expression — UCEC

Explore this box plot interactively →