PDZRN3-AS1

Across TCGA pan-cancer cohorts, PDZRN3-AS1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated PDZRN3-AS1 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher PDZRN3-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated PDZRN3-AS1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and PAAD show a favorable association.

LUAD, PAAD, and READ are the cancer types where PDZRN3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	All	0.801	0.621	<.001	57	view →
PAAD	DFS	Tertile	All	0.625	0.410	<.001	54	view →
READ	DFS	Tertile	III,IV	0.273	0.727	.001	50	view →
STAD	DFS	Median	IV	0.710	0.187	.002	36	view →
THYM	DFS	Tertile	All	0.582	0.947	<.001	36	view →
KIRC	DFS	Tertile	III,IV	0.797	0.566	.012	34	view →
BLCA	OS	Tertile	II,III,IV	0.220	0.488	.005	24	view →
KICH	DFS	Quartile	II,III,IV	0.234	0.827	.001	14	view →
GBM	DFS	Median	All	0.305	0.194	.006	12	view →
ACC	DFS	Tertile	All	0.761	0.338	.035	12	view →
UCEC	OS	Tertile	III,IV	0.980	0.804	.028	12	view →
BRCA	DFS	Median	III,IV	0.941	0.838	.018	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

PDZRN3-AS1–LUAD (DFS)

Open the LUAD breakdown →