PDZD7

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PDZD7 mutation is significantly associated with the RNA expression of many other genes, with 1,287 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PDZD7-associated genes across cancer lineages are RNU1-20P, CXorf66, and RNU6-1067P. Each is linked with PDZD7 in more than 2 cancer types. Because this analysis shows association rather than direction, both PDZD7-to-partner and partner-to-PDZD7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDZD7→partner) and Y-score (partner→PDZD7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCARNU1-20P →+0.609+4.995<.001<.00133
SCLCCXorf66 →+0.141+5.624<.001.00332
LIHCRNU6-1067P →+0.502+5.108<.001.00832
LIHCRN7SKP223 →+0.584+5.033<.001.00932
LIHCLINC02353 →+0.085+5.355<.001.00532
UCECRPL23AP90 →+0.328+2.556.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,287 associations by consensus.

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