PDZD3

Across TCGA patient cohorts, PDZD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,151 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible PDZD3-associated GO terms across cancer lineages are Glycerolipid biosynthetic process, Monosaccharide metabolic process, and Glucose metabolic process. Each is linked with PDZD3 in more than 22 cancer types. Because this analysis shows association rather than direction, both PDZD3-to-partner and partner-to-PDZD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glycerolipid biosynthetic process grouped by PDZD3-low versus PDZD3-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PDZD3→partner) and Y-score (partner→PDZD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Glycerolipid biosynthetic process →	+0.048	+0.659	<.001	<.001	3	23
ESCA	Monosaccharide metabolic process →	+0.044	+0.535	<.001	<.001	3	22
ESCA	Glucose metabolic process →	+0.046	+0.566	.001	<.001	3	22
ESCA	Glycerophospholipid biosynthetic process →	+0.043	+0.626	<.001	<.001	3	22
ESCA	Thioester metabolic process →	+0.044	+0.752	<.001	<.001	3	21
KIRC	Protein deacetylation →	+0.039	+1.078	<.001	<.001	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,151 associations by consensus.

Glycerolipid biosynthetic process by PDZD3 expression — ESCA

Explore this box plot interactively →