PDZD3

Across TCGA cell cohorts, PDZD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,168 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PDZD3-associated GO terms across cancer lineages are Response to sodium phosphate, Regulation of myoblast fusion, and Negative regulation of myoblast fusion. Each is linked with PDZD3 in more than 6 cancer types. Because this analysis shows association rather than direction, both PDZD3-to-partner and partner-to-PDZD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to sodium phosphate grouped by PDZD3-low versus PDZD3-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PDZD3→partner) and Y-score (partner→PDZD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Response to sodium phosphate →	-0.244	-1.182	.001	.002	3	7
BLOOD_Lymphoma	Regulation of myoblast fusion →	+0.082	+0.040	<.001	.002	3	7
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.084	+0.043	.002	.005	3	6
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.129	+0.066	<.001	.007	3	6
KIDNEY	Positive regulation of calcium ion import →	-0.143	-1.186	<.001	.001	3	6
STOMACH	Regulation of clathrin coat assembly →	+0.290	+2.226	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,168 associations by consensus.

Response to sodium phosphate by PDZD3 expression — KIDNEY

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