PDZD2

Across TCGA patient cohorts, PDZD2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,290 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PDZD2-associated proteins across cancer lineages are PDZD2_S1270, PDZD2_S1005, and PDZD2_S2489. Each is linked with PDZD2 in more than 8 cancer types. Because this analysis shows association rather than direction, both PDZD2-to-partner and partner-to-PDZD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDZD2 versus PDZD2_S1270 in LSCC, with a Pearson correlation of 0.68.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PDZD2→partner) and Y-score (partner→PDZD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PDZD2_S1270 →	+1.183	+0.878	<.001	<.001	3	9
LUAD	PDZD2_S1005 →	+1.532	+0.988	<.001	<.001	3	8
PDAC	PDZD2_S2489 →	+1.273	+1.225	.001	<.001	3	8
BRCA	PDZD2_S491 →	+1.440	+1.571	<.001	<.001	3	8
GBM	PDZD2_S920 →	+0.853	+1.461	<.001	<.001	3	8
GBM	PDZD2_S2341 →	+1.257	+1.609	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,290 associations by consensus.

PDZD2 vs PDZD2_S1270 — LSCC

Explore this scatter interactively →