PDZD2

Across TCGA patient cohorts, PDZD2 protein abundance is significantly associated with the RNA expression of many other genes, with 15,677 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PDZD2-associated genes across cancer lineages are RGCC, MYCT1, and RHOJ. Each is linked with PDZD2 in more than 4 cancer types. Because this analysis shows association rather than direction, both PDZD2-to-partner and partner-to-PDZD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDZD2 versus RGCC in BRCA, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDZD2→partner) and Y-score (partner→PDZD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RGCC →	+1.003	+0.456	<.001	<.001	3	5
BRCA	MYCT1 →	+0.714	+0.475	.003	<.001	3	4
GBM	RHOJ →	+0.880	+0.470	.001	<.001	3	4
BRCA	CD36 →	+1.526	+0.467	.002	<.001	3	4
BRCA	TACC1 →	+0.779	+0.358	.004	.003	3	4
LUAD	ESAM →	+0.806	+0.411	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,677 associations by consensus.

PDZD2 vs RGCC — BRCA

Explore this scatter interactively →