PDXK

Across TCGA patient cohorts, PDXK RNA expression is significantly associated with the protein abundance of many other proteins, with 10,215 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PDXK-associated proteins across cancer lineages are P4HA2, RPS6KA5, and SERPINH1. Each is linked with PDXK in more than 5 cancer types. Because this analysis shows association rather than direction, both PDXK-to-partner and partner-to-PDXK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDXK versus P4HA2 in PDAC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PDXK→partner) and Y-score (partner→PDXK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	P4HA2 →	+0.764	+0.448	<.001	<.001	3	6
LSCC	RPS6KA5 →	-0.414	-0.511	.001	.001	3	4
BRCA	SERPINH1 →	+0.620	+0.684	<.001	<.001	3	4
BRCA	GART →	+0.284	+0.567	<.001	<.001	3	4
BRCA	MET →	+0.926	+0.773	<.001	<.001	3	4
PDAC	TTYH3_S496 →	+0.496	+0.287	.005	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,215 associations by consensus.

PDXK vs P4HA2 — PDAC

Explore this scatter interactively →