PDXK

Across TCGA patient cohorts, PDXK protein abundance is significantly associated with the RNA expression of many other genes, with 17,946 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PDXK-associated genes across cancer lineages are RPS17, NOP56, and IL4I1. Each is linked with PDXK in more than 5 cancer types. Because this analysis shows association rather than direction, both PDXK-to-partner and partner-to-PDXK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDXK versus RPS17 in HNSC, with a Pearson correlation of -0.24.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDXK→partner) and Y-score (partner→PDXK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RPS17 →	-0.411	-0.205	.005	.003	3	6
LSCC	NOP56 →	-0.654	-0.317	<.001	<.001	3	5
UCEC	IL4I1 →	+0.876	+0.292	.004	.002	3	5
HNSC	DOCK8 →	+0.762	+0.224	.001	<.001	3	5
HNSC	SNRPB →	-0.917	-0.212	.001	<.001	3	5
LUAD	TXNL4A →	-0.426	-0.254	<.001	.008	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,946 associations by consensus.

PDXK vs RPS17 — HNSC

Explore this scatter interactively →