PDXDC1

Across TCGA patient cohorts, PDXDC1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,420 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible PDXDC1-associated genes across cancer lineages are MLPH, SMIM22, and AGR2. Each is linked with PDXDC1 in more than 7 cancer types. Because this analysis shows association rather than direction, both PDXDC1-to-partner and partner-to-PDXDC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDXDC1 versus MLPH in BRCA, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDXDC1→partner) and Y-score (partner→PDXDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MLPH →	+1.840	+0.326	<.001	<.001	3	8
BRCA	SMIM22 →	+1.455	+0.576	<.001	<.001	3	8
BRCA	AGR2 →	+2.304	+0.343	<.001	<.001	3	7
UCEC	LRRC31 →	+1.607	+0.395	<.001	<.001	3	7
UCEC	SAR1B →	+0.433	+0.323	<.001	<.001	3	7
OV	TXNDC11 →	+0.474	+0.421	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,420 associations by consensus.

PDXDC1 vs MLPH — BRCA

Explore this scatter interactively →